HPMCマトリックス錠の非破壊的溶出予測のためのアニー支援UVイメージング
Orsolya Péterfi1, Lilla Alexandra Mészáros1, Bence Szabó-Szőcs1
1Department of Organic Chemistry and Technology, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem Rkp. 3., H-1111 Budapest, Hungary.
International journal of pharmaceutics
|February 7, 2026
まとめ
人工ニューラルネットワーク(ANN)と組み合わせたUVイメージングは、ヒドロキシプロピルセルロース(HPMC)含有量を分析することにより、徐放錠からの薬物溶出を正確に予測します。この非破壊的方法は、製剤変更の迅速な評価を提供します。
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