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猫における片側性副耳介軟骨腫:症例報告
Florine Brun1, Morgane Pertuis1, Noëlle Cochet-Faivre2
1Unité d'Histologie et d'Anatomie Pathologique, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort, France.
まとめ
副耳介軟骨腫は、まれな先天性耳奇形であり、猫で初めて特定された。これらの所見は、この外耳奇形の既知の獣医学的症例を拡張するものである。
科学分野:
- 獣医学病理学
- 比較解剖学
- 先天性奇形
背景:
- 副耳介軟骨腫は、第一咽頭弓から発生する外耳の先天性奇形である。
- ヒトでは、常染色体優性遺伝を伴う先天性症候群に関連する場合がある。
- 以前の獣医学的報告は少なく、犬での報告例は1例のみである。
研究 の 目的:
- 猫の患者における副耳介軟骨腫の最初の記録症例を報告すること。
- 猫におけるこのまれな先天性奇形の詳細な組織病理学的記述を提供すること。
- この病変に遭遇した病理医のための診断上の考慮事項を強調すること。
主な方法:
- 猫の耳前部にある3つの皮膚外胚葉性病変の臨床観察。
- 提出された2つの病変の組織学的検査。
- 表皮構造、膠原線維性間質、付属器構造、および軟骨を含む組織組成の顕微鏡分析。
主要な成果:
- 2.5歳のヨーロッパンショートヘア猫に、副耳介軟骨腫と診断された2つの病変が確認された。組織学的には、病変は付属器構造と表皮ひだを持つ膠原線維性のコアを示し、1つには弾性軟骨が含まれていた。表皮は正常な厚さで、わずかに色素沈着していた。
結論:
- 副耳介軟骨腫は猫で初めて報告され、獣医学におけるその既知の発生例を拡張するものである。
- 組織病理学的所見は、猫におけるこのまれな状態の診断の基礎を提供する。
- 軟骨がない場合や、サンプルの位置が不明な場合には、正確な診断が困難な場合がある。
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