Free-breathing Three-dimensional MR Cholangiopancreatography Using Centric k-space Encoding Improved Gallbladder
Junya Tsuzaki1, Taiki Nozaki1,2, Daiki Ito3,4
1Department of Radiology, Keio University School of Medicine, Tokyo, Japan.
まとめ
MRCP-CORE, a new free-breathing MRI technique, significantly improves gallbladder visualization compared to conventional MRCP. This novel method offers a robust alternative to breath-hold techniques for enhanced diagnostic imaging.
科学分野:
- 放射線学および医用画像処理;消化器病学;医用生体工学
背景:
- 磁気共鳴胆管膵管造影(MRCP)は、胆汁濃縮による信号損失によって制限されることがあります。グラディエントアンドスピンエコー(GRASE)MRCPは信号を改善しますが、息止めが必要です。患者の快適性と画質のために、自由呼吸MRCP技術の開発は不可欠です。
研究 の 目的:
- 中心k空間エンコーディング(MRCP-CORE)を用いた新しい自由呼吸シーケンスのMRCPを開発および評価すること。MRCP-COREの胆嚢視認能力を従来のMRCPおよびGRASE MRCPと比較して評価すること。胆汁の濃度が異なるMRCPシーケンス全体で胆嚢の視認性に与える影響を調査すること。
主な方法:
- 3Tシステムで3つのMRCPシーケンス(MRCP-CORE、従来のMRCP、GRASE MRCP)を受けた100人の患者を対象とした前向き研究。解剖学的構造の視認性、アーチファクト、および全体的な画質に関する独立した放射線科医による評価。SNR、コントラスト対雑音比、およびコントラスト比の定量的測定。フリードマンおよびヨンクヘール・テルストラ検定を用いた統計分析。
主要な成果:
- MRCP-COREは、従来のMRCPおよびGRASE MRCPと比較して有意に高い信号対雑音比(SNR)(それぞれ20.9対17.3対15.8、P < 0.001)を示しました。胆嚢の視認性は、MRCP-COREが従来のMRCPよりも有意に改善され(P = 0.02)、GRASE MRCPと同等でした(P = 1.00)。胆汁の濃度は、従来のMRCPにおける胆嚢の視認性に影響を与えましたが(P < 0.001)、MRCP-CORE(P = 0.12)またはGRASE MRCP(P = 0.43)では影響しませんでした。
結論:
- MRCP-COREは、従来のMRCPと比較して胆嚢の描出を改善します。MRCP-COREは、息止めGRASE MRCPに代わる堅牢な自由呼吸代替手段を提供します。この新しいシーケンスは、MRCPにおける胆汁濃度に関連する限界を克服します。
関連する概念動画
Gallbladder
2.3K
The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
2.3K
Breathing
64.6K
The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
64.6K
Serum Laboratory Studies, Stool Test, Breath Test
892
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
892
Diseases of the Liver and Gallbladder
2.0K
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
2.0K
Design of Columns under a Centric Load
566
The design of columns under centric load is a fundamental aspect of structural engineering and is critical for ensuring the stability and integrity of structures. Euler's and Secant's formulas are central to understanding and calculating the critical load and deformation behaviors of columns, providing a basis for safe and effective structural design.
Euler's formula is applicable under the assumption that the column is a perfect, straight, homogenous prism, and it is operating...
Euler's formula is applicable under the assumption that the column is a perfect, straight, homogenous prism, and it is operating...
566
Encoding
869
Information enters the brain through encoding, which is the input of information into the memory system. Once sensory information is received from the environment, the brain labels or codes it. The information is then organized with similar information and connected to existing concepts. Encoding occurs through automatic processing and effortful processing.
Automatic processing involves the encoding of details like time, space, frequency, and the meaning of words, usually done without conscious...
Automatic processing involves the encoding of details like time, space, frequency, and the meaning of words, usually done without conscious...
869


