幻肢運動のイントラニューラル記録からのデコーディング
Cecilia Rossi1, Marko Bumbasirevic2, Paul Čvančara3
1Institute of Neuroinformatics, University of Zurich and ETH Zurich, Zurich, Switzerland.
Nature communications
|February 8, 2026
まとめ
坐骨神経内のイントラニューラル電極は、切断者における幻肢運動をデコードすることにより、義肢制御を可能にしました。このアプローチは、高度な双方向ニューラルプロテーゼの可能性を示しています。
科学分野:
- 神経科学
- 生物医学工学
- 義肢
背景:
- 四肢の喪失は感覚運動障害をもたらし、多くの場合義肢を必要とします。
- 義肢制御のための直接的な神経記録は、低信号振幅や神経インターフェースの困難さなどの課題に直面しています。
主な方法:
- 2人の大腿転移切断者の遠位坐骨神経枝への横断的筋内マルチチャネル電極のインプラテーション。
- 幻肢の膝、足首、つま先の動きに関連する多単位活動の記録。
- 運動予測のためのスパイキングニューラルネットワーク(SNN)ベースのデコーダーの利用。
結論:
- 坐骨神経からのイントラニューラル記録は、幻肢運動をデコードできます。
- この技術は、双方向の神経制御された義肢システムの開発をサポートします。
- 神経内の運動および感覚マップの早期分離が観察されました。
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