犬の顕著な核多形性を示す皮膚上皮向性リンパ腫
Da-Hyeon Lee1, Woo-Jin Song2, Jongtae Cheong3
1College of Veterinary Medicine, Jeju National University, Jeju 63243, Korea.
Journal of veterinary science
|February 9, 2026
まとめ
この症例報告は、他の癌を模倣した異常な細胞的特徴を持つ、まれな犬の皮膚上皮向性リンパ腫(CEL)について詳述しています。この非定型的な犬リンパ腫の提示を理解するには、さらなる研究が必要です。
科学分野:
- 獣医病理学; 犬腫瘍学; 皮膚科学
背景:
- 皮膚上皮向性リンパ腫(CEL)は、犬ではまれながんです。異常な細胞形状や免疫マーカーを含む非定型的な提示は、まれにしか文書化されていません。
主な方法:
- 口腔および皮膚病変を有するゴールデンレトリバーに対し、吸引細胞診および組織病理検査を実施しました。免疫表現型分類およびクローナリティ評価のために、フローサイトメトリーおよび抗原受容体再配列のPCRを使用しました。
結論:
- 本症例は、犬のCELにおける非定型的な臨床病理学的特徴を示しています。本所見は、正確な診断と疾患生物学の理解のために高度な診断の重要性を強調しています。
関連する概念動画
Bone Markings
8.2K
Bones have various surface features that help form joints and attach to other soft tissues. Depending on the function, bone markings are categorized into articulating projections, processes for attachment, depressions, and openings.
Articulating Projections
Articulating projections are found where two bones meet to form a joint. These structures are usually found at the ends of bones. The largest articulation is a rounded projection called the head, supported by a narrow neck at the ends of...
Articulating Projections
Articulating projections are found where two bones meet to form a joint. These structures are usually found at the ends of bones. The largest articulation is a rounded projection called the head, supported by a narrow neck at the ends of...
8.2K
Nuclear Stability
23.4K
Protons and neutrons, collectively called nucleons, are packed together tightly in a nucleus. With a radius of about 10−15 meters, a nucleus is quite small compared to the radius of the entire atom, which is about 10−10 meters. Nuclei are extremely dense compared to bulk matter, averaging 1.8 × 1014 grams per cubic centimeter. If the earth’s density were equal to the average nuclear density, the earth’s radius would be only about 200 meters.
To hold positively charged protons together...
To hold positively charged protons together...
23.4K
Nuclear Fusion
33.9K
The process of converting very light nuclei into heavier nuclei is also accompanied by the conversion of mass into large amounts of energy, a process called fusion. The principal source of energy in the sun is a net fusion reaction in which four hydrogen nuclei fuse and ultimately produce one helium nucleus and two positrons.
A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...
A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...
33.9K
Non-nuclear Inheritance
23.3K
Most DNA resides in the nucleus of a cell. However, some organelles in the cell cytoplasm—such as chloroplasts and mitochondria—also have their own DNA. These organelles replicate their DNA independently of the nuclear DNA of the cell in which they reside. Non-nuclear inheritance describes the inheritance of genes from structures other than the nucleus.
23.3K
Nuclear Export of mRNA
8.8K
Before mRNAs are exported to the cytoplasm, it is crucial to check each mRNA for structural and functional integrity. Eukaryotic cells use several different mechanisms, collectively known as mRNA surveillance, to look for irregularities in mRNAs. Irregular or aberrant mRNA are rapidly degraded by various enzymes. If a defective mRNA escapes the surveillance, it would be translated into a protein which would either be non-functional or not function properly. One of the primary irregularities in...
8.8K
Nuclear Transmutation
20.7K
Nuclear transmutation is the conversion of one nuclide into another. It can occur by the radioactive decay of a nucleus, or the reaction of a nucleus with another particle. The first manmade nucleus was produced in Ernest Rutherford’s laboratory in 1919 by a transmutation reaction, the bombardment of one type of nuclei with other nuclei or with neutrons. Rutherford bombarded nitrogen-14 atoms with high-speed α particles from a natural radioactive isotope of radium and observed...
20.7K


