関連する実験動画

Updated: Feb 11, 2026

Detecting Anastasis In Vivo by CaspaseTracker Biosensor

Detecting Anastasis In Vivo by CaspaseTracker Biosensor

Published on: February 1, 2018

アナスタシス：現実かフィクションか？

Y S Kim¹, K V Kovalskaya¹, S L Malov²

¹Institute of Biomedical Chemistry, Moscow, Russia.

Bulletin of experimental biology and medicine

|February 9, 2026

Abstract:

Increased resistance to the apoptosis-inducing stimuli, as well as the reversibility of the process of cell death, are currently recognized as the mechanisms that tumor cells use for survival, maintenance of malignancy, and metastasis. The term "anastasis" was introduced to describe the reversibility of cell death. We have previously shown that mesenchymal stem cells (MSCs) are resistant to receptor-mediated apoptosis. In this work, the possibility of anastasis in three types of mesenchymal cells (human liver and placental MSCs and skin fibroblasts) was studied after exposure to common cell death inducers ethanol, staurosporine, or doxorubicin. We have shown that restoration of cell morphology and proliferation occurs after treatment with non-lethal doses of ethanol and low concentration of doxorubicin, while staurosporine at non-lethal concentrations produces an irreversible cytostatic effect.

キーワード:

アナスタシスアポトーシス細胞死間葉系幹細胞皮膚線維芽細胞

さらに関連する動画

Strategies for Tracking Anastasis, A Cell Survival Phenomenon that Reverses Apoptosis

Strategies for Tracking Anastasis, A Cell Survival Phenomenon that Reverses Apoptosis

Published on: February 16, 2015

Virtual Reality Experiments with Physiological Measures

Virtual Reality Experiments with Physiological Measures

Published on: August 29, 2018

関連する概念動画

Obedience

Obedience

According to obedience research, we may harm others under the forceful pressures of an authority figure (Milgram, 1974). How about if the inappropriate orders were delivered with less force? The increasing interdependence between nurses and physicians compelled Hofling and his colleagues to explore nurses’ reactions to a potentially harmful medical request made by the perceived authority figure, the doctor (Hofling, Brotzman, Dalrymple, Graves, & Pierce, 1966). In this situation,...

Cognitive Dissonance

Cognitive Dissonance

Social psychologists have documented that feeling good about ourselves and maintaining positive self-esteem is a powerful motivator of human behavior (Tavris & Aronson, 2008). In the United States, members of the predominant culture typically think very highly of themselves and view themselves as good people who are above average on many desirable traits (Ehrlinger, Gilovich, & Ross, 2005). Often, our behavior, attitudes, and beliefs are affected when we experience a threat to our...

The Sense of Self: Reflected Self-Appraisal and Social Comparison

The Sense of Self: Reflected Self-Appraisal and Social Comparison

According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...

Blind Procedures

Blind Procedures

Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...