関連する実験動画

Updated: Feb 11, 2026

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Published on: April 19, 2024

2型糖尿病患者における血糖コントロールのための食事併用運動介入の効果：ランダム化比較試験のメタアナリシス

Xiaoyi Huang^1,2, Guihao Huang³, Man Jiang²

¹Department of Public Health and Medicinal Administration, Faculty of Health Sciences, University of Macau, Macau, China.

The Journal of sports medicine and physical fitness

|February 10, 2026

要旨

Introduction:

To systematically analyze the effect of diet combined with exercise intervention on blood glucose control in patients with type 2 diabetes.

Evidence Acquisition:

Six databases including PubMed, The Cochrane Library, Web of Science, EMBASE, MEDLINE and CNKI were searched from establishment to September 2024. Randomized Control Trial (RCT) articles that met the inclusion and exclusion criteria were screened. Meta-analysis was performed using Review Manager 5.3 software. The quality of the literature was assessed using the Cochrane Handbook of Systematic Reviews. Subgroup analysis and sensitivity analysis were used to find the source of heterogeneity.

Evidence Synthesis:

Sixteen studies were included, with a total of 7212 patients with type 2 diabetes. There were 3678 cases in the intervention group and 3534 cases in the control group. The results of meta-analysis showed that dietary combined exercise intervention significantly improved fasting blood glucose (MD=-0.39, 95% CI: -0.72~-0.06, P=0.02) and 2-hour postprandial blood glucose (MD=-1.67, 95% CI: -3.62~0.27, P=0.09), glycosylated hemoglobin, HbA1c (MD=-0.49, 95% CI: -1.27~-0.33, P<0.001), body weight (MD=-2.47, 95% CI: -4.82~-0.13, P=0.04), body mass (MD=-3.64, 95% CI: -4.07~-3.21, P<0.001), SBP (MD=-2.1, 95% CI: -4.30~0.28, P=0.09), DBP (MD=-0.93, 95% CI: -1.88~0.02, P=0.05), total cholesterol (MD=17, 95% CI: -0.02~0.35, P=0.07), triglyceride (MD=-0.08, 95% CI: -0.15~-0.01, P=0.03), QOL (MD=3.83, 95% CI: 0.69~6.98, P=0.02). Body Mass Index (BMI) (MD=-0.4, 95% CI: -0.32~0.24, P=0.79), waist circumference (MD=-1.4, 95% CI: -4.94~1.25, P=0.24), HDL (MD=-0.02, 95% CI: -0.08~0.03, P=0.43), LDL (MD=12, 95% CI: -0.37~0.61, P=0.63) may be due to insufficient patient compliance, short intervention time, or insufficient study sample size to detect significant improvement.

Conclusions:

Diet combined with exercise intervention has significant effect on blood glucose control in patients with type 2 diabetes, and can significantly reduce HbA1c, fasting blood glucose, 2 h postprandial blood glucose, body weight, body mass, total cholesterol, triglyceride, SBP, DBP and QOL. Therefore, it is recommended that exercise combined with dietary intervention for at least 3 to 6 months can better improve the blood glucose indicators in patients with type 2 diabetes.

キーワード:

2型糖尿病血糖コントロール食事療法運動療法メタアナリシスランダム化比較試験 HbA1c 体重減少生活の質

さらに関連する動画

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health

Published on: December 1, 2023

Author Spotlight: Integrating Tai Chi with Mindfulness Training to Achieve an Effective Mind-Body Exercise

Author Spotlight: Integrating Tai Chi with Mindfulness Training to Achieve an Effective Mind-Body Exercise

Published on: July 14, 2023

関連する概念動画

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...

Diabetes Mellitus: Type 2 and Gestational

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...

Combinatorial Gene Control

Combinatorial Gene Control

Combinatorial gene control is the synergistic action of several transcriptional factors to regulate the expression of a single gene. The absence of one or more of these factors may lead to a significant difference in the level of gene expression or repression.
The expression of more than 30,000 genes is controlled by approximately 2000-3000 transcription factors. This is possible because a single transcription factor can recognize more than one regulatory sequence. The specificity in gene...

meta-Directing Deactivators: –NO2, –CN, –CHO, –&NoBreak;CO2R, –COR, –CO2H

meta-Directing Deactivators: –NO₂, –CN, –CHO, –⁠CO₂R, –COR, –CO₂H

All meta-directing substituents are deactivating groups. These substituents withdraw electrons from the aromatic ring, making the ring less reactive toward electrophilic substitution. For example, the nitration of nitrobenzene is 100,000 times slower than that of benzene because of the deactivating effect of the nitro group. The first step in an electrophilic aromatic substitution is the addition of an electrophile to form a resonance-stabilized carbocation. The energy diagrams for...

Control System Problem

Control System Problem

In an open-loop system, such as a basic thermostat, the poles of the transfer function influence the system's response but do not determine its stability. However, when feedback is introduced to form a closed-loop system, such as an advanced thermostat that adjusts heating based on room temperature, stability is governed by the new poles of the closed-loop transfer function.
When forming a closed-loop system, issues can arise if the poles cross into the unstable region, leading to potential...

Control Systems

Control Systems

Control systems are everywhere in contemporary society, influencing diverse applications from aerospace to automated manufacturing. These systems can be found naturally within biological processes, such as blood sugar regulation and heart rate adjustment in response to stress, as well as in man-made systems like elevators and automated vehicles. A control system is essentially a network of subsystems and processes that collaboratively convert specific inputs into desired outputs.
At the heart...