高齢者の下肢手術における術後せん妄予測のための単純な指標としての握力:前向き診断的評価
Hyo Sung Kim1, Seok Kyeong Oh1, Young Sung Kim1
1Department of Anesthesiology and Pain Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Anesthesia and pain medicine
|February 10, 2026
まとめ
握力が低い(GS)ことは、下肢手術を受ける高齢患者における術後せん妄(POD)の有意な予測因子である。この単純なスクリーニングツールは、より良い患者転帰のためにリスクのある個人を特定するのに役立つ。
科学分野:
- 老年医学
- 外科的転帰
- 診断スクリーニング
背景:
- 握力(GS)は加齢とともに低下し、サルコペニアとフレイルを示唆し、術後せん妄(POD)のリスクを高める。
- 移動能力の制限により、下肢手術を受ける高齢患者のフレイルの評価は困難である。
- POD予測のためのGSのような単純なスクリーニングツールの調査は非常に重要である。
研究 の 目的:
- 術前の握力(GS)が、下肢手術を受ける高齢患者における術後せん妄(POD)を独立して予測するかどうかを判断すること。
- 韓国人集団におけるPOD予測のための低いGSの定義に最も適切な基準を特定すること。
主な方法:
- 下肢手術を受けた65歳以上の患者150名を対象とした前向き研究。
- アジアサルコペニア作業部会(AWGS)基準などを用いて、術前の握力(GS)を測定し、サルコペニアを診断した。
- 術後せん妄(POD)は集中治療室用せん妄評価法(Confusion Assessment Method for the Intensive Care Unit)を用いて評価した。ロジスティック回帰およびROC曲線分析を実施した。
主要な成果:
- 術後せん妄(POD)は患者の11.3%に発生した。PODを有する17例中13例は握力が低かった(GS)。アジアサルコペニア作業部会(AWGS)基準は、低いGSの予測精度が最も高かった(AUC = 0.796)。低い握力(GS)はPODの唯一の独立した予測因子であった(OR = 15.543、P < 0.001)。これは他の臨床変数よりも優れていた。
結論:
- 握力(GS)は、術後せん妄(POD)の単純かつ信頼性の高い独立した予測因子である。
- 術前のGS評価は、下肢手術後のPODのリスクが高い高齢患者を特定するのに役立つ可能性がある。
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