誘発性中絶,流産,乳がんのリスク - フィンランドからの登録ベースの研究

Sushmita Katuwal^1,2, Jaana Männistö³, Maarit Niinimäki³

¹Unit of Health Sciences, Faculty of Social Medicine, Tampere University, Tampere, Finland.

Acta obstetricia et gynecologica Scandinavica

|February 11, 2026

まとめ

誘発性中絶や流産歴は,乳がんのリスクを増やさない. この大規模なフィンランド登録調査は,イベント数や年齢に関係なく,更年期前のまたは更年期後の女性との関連性が見つかりませんでした.

科学分野:

生殖器保健は,生殖器の健康についてです.
腫瘍学腫瘍学
エピデミオロジーエピデミオロジー

背景:

誘発性中絶,流産,乳がんのリスクとの関係は,しばしば誤った情報によって曇った議論の話題です.
この主題に関する以前の研究は,しばしば小さなサンプルサイズと自己報告データへの依存によって制限されていました.
フィンランドの高品質の登録データは,これらの協会を厳格に評価する機会を提供します.

研究の目的:

誘発性中絶と乳がんリスクとの関連を調査する.
流産と乳がんのリスクとの関連を調べる.
閉経前と閉経後の女性のリスクを区分する.

主な方法:

フィンランドの国立登録データを活用した人口ベースのケース・コントロール研究.
乳がんの女性31,687人と,マッチングした対照群158,433人を含む.
誘導性中絶,流産,出産,ホルモン療法,SES,職業に関するデータを収集し,多変量条件ロジスティック回帰を用いて分析した.

主要な成果:

妊娠中絶歴のある女性では,乳がんの確率比 (OR) の増加は観察されなかった (閉経前OR: 1.00,閉経後のOR: 0.95).
妊娠中絶歴のある女性では,乳がんに対するORの増加は認められなかった (閉経前 OR:1.02,閉経後の OR:0.92).
リスクは,イベントの数や最初のイベントの時点の年齢によって有意に変化しませんでした.

結論:

誘発性中絶歴は,その後の乳がんのリスクの増加と関連していません.
流産歴は,その後の乳がんのリスクの増加と関連していません.
これらの発見は,イベントの数やイベントの時点での女性の年齢に関係なく真実です.

キーワード:

そして閉経後の乳がん.妊娠初期に妊娠が始まる.誘発性中絶による中絶流産流産流産閉経前乳がん閉経前乳がん

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