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Sinusoidal Sources01:18

Sinusoidal Sources

1.2K
Direct current (DC) refers to an electric current that flows in a single direction, maintaining a constant polarity. This is in contrast to alternating current (AC), which periodically changes its direction and magnitude. AC forms the backbone of modern electricity transmission and distribution systems due to its efficient long-distance transmission capabilities.
In homes, the power supplies use sinusoidal sources to provide electricity. These sources generate a voltage that varies sinusoidally...
1.2K
AC Sources01:20

AC Sources

4.1K
Direct current is a flow of electric charge in only one direction and has a steady state of constant voltage in the circuit. Rectifiers, batteries, commutator-equipped generators, and fuel cells are some examples of devices that generate direct current. Nowadays, most applications use a time-varying voltage source. Alternating current is a flow of electric charge that periodically reverses direction. An alternating current is produced by an alternating emf that is generated in a power plant. If...
4.1K
Sources of Law01:26

Sources of Law

1.9K
Laws form the essential rules set by governing authorities to shape and control societal behavior. In nursing, laws guide actions, safeguard patient rights, define nurses' scope of practice, and maintain professional standards. Understanding the legal framework governing nursing involves recognizing four primary sources of law: constitutional, statutory, administrative (regulatory), and common law.
Constitutional law is foundational, deriving from federal and state constitutions, and...
1.9K
Source Transformation01:15

Source Transformation

11.8K
Source transformation is a fundamental technique employed in circuit analysis, offering a valuable tool for simplifying complex electrical circuits. This technique involves the replacement of either a voltage source in series with a resistor by a current source in parallel with a resistor, or vice versa. The key concept here is that when the original sources are deactivated (turned off), the equivalent resistance at the circuit's end terminals remains the same.
It is essential to note that when...
11.8K
Depth Perception and Spatial Vision01:15

Depth Perception and Spatial Vision

2.1K
Depth perception is the ability to perceive objects three-dimensionally. It relies on two types of cues: binocular and monocular. Binocular cues depend on the combination of images from both eyes and how the eyes work together. Since the eyes are in slightly different positions, each eye captures a slightly different image. This disparity between images, known as binocular disparity, helps the brain interpret depth. When the brain compares these images, it determines the distance to an object.
2.1K
Multiple Voltage Sources01:25

Multiple Voltage Sources

1.8K
Generally, a single battery is not enough to power some devices. In such cases, batteries can be combined in two ways: in series or in parallel.
In series, the positive terminal of one battery is connected to the negative terminal of another battery. Hence, the voltage of each battery is added to give the net voltage, which is increased because each battery boosts the electrons that enter it. The same current flows through each battery because they are connected in series.
Batteries are...
1.8K

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Updated: Feb 12, 2026

An Open-Source Virtual Reality System for the Measurement of Spatial Learning in Head-Restrained Mice
08:59

An Open-Source Virtual Reality System for the Measurement of Spatial Learning in Head-Restrained Mice

Published on: March 3, 2023

2.8K

LipidLocator: 空間的脂質学のためのオープンソースのシャイニーウェブアプリケーション.

Prateek Arora1,2, Simon Isfort3,4, Nick Kirschke1,2

  • 1Institute of Anatomy, University of Bern, Bern, 3012, Switzerland.

Bioinformatics advances
|February 11, 2026
PubMed
まとめ

LipidLocatorは,質量スペクトロメトリ画像データ分析と脂質アノテーションを統合することにより,空間的脂質学を簡素化する新しいオープンソースツールです. このユーザーフレンドリーなアプリケーションは,脂質分布の研究を通じて組織構造と機能を理解するのに役立ちます.

さらに関連する動画

Applications for Open Source Microplate-Compatible Illumination Panels
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Applications for Open Source Microplate-Compatible Illumination Panels

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On-Site Sampling and Extraction of Brain Tumors for Metabolomics and Lipidomics Analysis
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On-Site Sampling and Extraction of Brain Tumors for Metabolomics and Lipidomics Analysis

Published on: May 31, 2020

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関連する実験動画

Last Updated: Feb 12, 2026

An Open-Source Virtual Reality System for the Measurement of Spatial Learning in Head-Restrained Mice
08:59

An Open-Source Virtual Reality System for the Measurement of Spatial Learning in Head-Restrained Mice

Published on: March 3, 2023

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Applications for Open Source Microplate-Compatible Illumination Panels
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Applications for Open Source Microplate-Compatible Illumination Panels

Published on: October 3, 2019

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On-Site Sampling and Extraction of Brain Tumors for Metabolomics and Lipidomics Analysis
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On-Site Sampling and Extraction of Brain Tumors for Metabolomics and Lipidomics Analysis

Published on: May 31, 2020

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科学分野:

  • バイオケミストリー バイオケミストリー
  • アナリティカル・ケミストリー (Analytical Chemistry) とは
  • バイオインフォマティックス

背景:

  • 空間的脂質学は,脂質の分布をマッピングすることによって,組織構造と機能の洞察を提供します.
  • 複雑な質量スペクトロメトリ画像 (MSI) データの分析は,統合されたMSI,MS,MS/MSパイプラインのための高信頼性アノテーションツールの限界のために困難です.

研究 の 目的:

  • 統一された空間的脂質学パイプラインのためのオープンソースのインタラクティブウェブアプリケーションを開発する.
  • MSI,MS,MS/MSのデータ分析を統合することにより,高信頼性の脂質アノテーションを容易にする.

主な方法:

  • LipidLocator,インタラクティブなShiny Webアプリケーションを開発しました.
  • 統合されたMSIデータ分析,標準化,空間クラスタリング,および差異的豊富な分析を含む.
  • MSおよびMS/MSベースの脂質アノテーションを単一のパイプラインで有効にしました.

主要な成果:

  • LipidLocatorは,ゼブラフィッシュ,ヒト腎臓がん,マウスの脳部位のDESI-MSIとAP-SMALDIデータを分析した.
  • 異なる解剖学的構造と組織サブ領域を分割する能力を実証しました.
  • 統合されたMSおよびMS/MSアノテーションを使用して,高信頼性の脂質プロファイルを生成しました.

結論:

  • LipidLocatorは,空間的脂質学のためのエンドツーエンド,オープンソースのパイプラインを提供します.
  • 様々な生物と脂質検出技術をサポートし,脂質画像の研究を強化しています.
  • このアプリケーションは,脂質代謝の研究のための貴重な,ユーザーフレンドリーなリソースとして機能します.