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Updated: Feb 12, 2026

Detection and Removal of Nuclease Contamination During Purification of Recombinant Prototype Foamy Virus Integrase
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Detection and Removal of Nuclease Contamination During Purification of Recombinant Prototype Foamy Virus Integrase

Published on: December 8, 2017

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プロトタイプ発泡性ウイルスEnvの構造誘導工学により,硫酸ヘパラン結合の主要な残留物を特定し,変換効率を高めています

Hee-Seung Shin1, Soo-Yeon Cho1, Yujin Kwon2,3

  • 1Department of Systems Biotechnology, Chung-Ang University, Anseong, Republic of Korea.

Frontiers in bioengineering and biotechnology
|February 11, 2026
PubMed
まとめ

プロトタイプ発泡性ウイルス (PFV) Envの構造誘導工学により,ヘパラン硫酸塩 (HS) の結合のための重要な残留物が見つかりました. 合理的な改変により,PFVの遺伝子転送効率が著しく向上し,この遺伝子配送プラットフォームを改善しました.

キーワード:
環境エンジニアリングは,遺伝子配達 遺伝子配達 遺伝子配達ヘパラン硫酸エパラン硫酸エパラン硫酸プロトタイプ発泡ウイルス.受容体結合ドメインは受容体結合ドメインである.トランスデュークション効率の効率化

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