白血病患者における後部結節性強膜炎:症例報告
Charifa Moussaddykine1, Laure Van Bol1, Joachim Van Calster2
1Department of Ophthalmology, Erasmus University Hospital, Brussels, Belgium.
Case reports in ophthalmology
|February 11, 2026
まとめ
この症例報告は、化学療法後の白血病患者における結節性後部強膜炎(NPS)を詳述する。治療により眼所見の部分的退縮が示され、免疫不全患者における徹底的な検査の必要性が強調された。
科学分野:
- 眼科学; 血液学; 免疫学
背景:
- 結節性後部強膜炎(NPS)はまれな炎症性眼疾患である。 化学療法および同種移植を受けている白血病患者は、眼の炎症性疾患を含む様々な合併症にかかりやすい。
研究 の 目的:
- 白血病患者における結節性後部強膜炎の困難な症例を記述すること。 免疫不全者におけるNPSの診断および管理戦略を議論すること。
主な方法:
- 観察的症例報告。 眼球Bモード超音波検査および脳磁気共鳴画像検査。 硝子体生検を伴う硝子体切除術。 全身検査および局所ステロイド、硝子体内注射、全身抗生物質による治療。
主要な成果:
- 患者は片側性の視力低下と痛みを呈した。 画像検査により、強膜結節、滲出性網膜剥離(ERD)、および漿液性脈絡膜剥離(SCD)を伴う後部強膜炎が明らかになった。 治療により、SCDの完全な退縮と、結節およびERDの部分的な退縮がもたらされた。
結論:
- 結節性後部強膜炎は、化学療法および同種移植後の白血病患者に発生する可能性がある。 免疫抑制患者における不明瞭な病因については、全身評価および潜在的な硝子体切除術と網膜下生検が重要である。
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