関連する実験動画

Updated: Feb 12, 2026

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness

Published on: May 3, 2018

マグネシウム枯渇スコアと動脈硬化の関連性：ブリジゲッラ心臓研究からのデータ

Federica Fogacci¹, Marina Giovannini¹, Elisa Grandi¹

¹Hypertension and Cardiovascular Risk Research Center, Medical and Surgical Sciences Department, Alma Mater Studiorum University of Bologna.

Journal of hypertension

|February 11, 2026

要旨

Background And Aims:

The magnesium depletion score (MDS) estimates magnesium deficiency risk by integrating dietary intake and physiological losses. This study evaluated the association between MDS and arterial stiffness in a rural Mediterranean population.

Methods:

We analyzed data from 2048 participants (49.2% men, 50.8% women) in the Brisighella Heart Study. MDS and arterial stiffness parameters - augmentation index (AIx) and carotid-femoral pulse wave velocity (cfPWV) - were assessed using validated methods. Multiple regression models adjusted for age and mean arterial pressure included sex, smoking, physical activity, BMI, heart rate, fasting glucose, low-density lipoprotein cholesterol (LDL-C), triglycerides, serum uric acid, estimated glomerular filtration rate (eGFR), and MDS.

Results:

An MDS at least 2 was observed in 51.6% of participants, more often in men (P < 0.001). Higher MDS was significantly associated with increased AIx and cfPWV in both sexes (P < 0.001). MDS remained an independent predictor of AIx (β = 0.087, P = 0.011) and cfPWV (β = 0.131, P = 0.013) after adjustment.

Conclusion:

Higher MDS values correlate with greater arterial stiffness, suggesting that magnesium imbalance may negatively affect vascular health.

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Depletion and Reconstitution of Macrophages in Mice

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