境界性パーソナリティ障害におけるアルコール使用障害の有病率：メタアナリシスおよびメタ回帰研究

This review examined the prevalence rate of alcohol use disorders (AUDs)-including heavy episodic drinking, heavy drinking, alcohol abuse, and alcohol dependence-among individuals with borderline personality disorder (BPD).

The primary objective of this meta-analysis and meta-regression study was to investigate the prevalence AUDs associated with BPD.

We searched PubMed, Google Scholar, Virtual Health Library (VHL/BVS), SciELO, LILACS, EMBASE, and PsycINFO for studies, reports, or abstracts published without language restrictions.

We searched for reports published from database inception through March 2024. This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and Meta-analysis Of Observational Studies in Epidemiology guidelines (MOOSE). Based on the extracted data, we performed meta-analyses and meta-regressions.

The final sample included 15 articles with 15,603 individuals aged 18 years or older with BPD. The prevalence of AUDs with BPD was 55.28%, while the prevalence of alcohol dependence (AD) was 44.59%, and alcohol abuse (AA) was 18.84%.

Our findings indicate a high prevalence of AUDs among individuals with BPD, underscoring the need for targeted prevention and treatment strategies. Integrated dual-diagnosis approaches addressing both disorders simultaneously are crucial for improving outcomes. This high prevalence has important implications for public health.