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Updated: Feb 12, 2026

Isotopic Effect in Double Proton Transfer Process of Porphycene Investigated by Enhanced QM/MM Method

Isotopic Effect in Double Proton Transfer Process of Porphycene Investigated by Enhanced QM/MM Method

Published on: July 19, 2019

光誘起プロトン移動および電子移動を介した未活性化アルケンの1,2-クロロチオ化

Chao Xie¹, Zemin Wang¹, Wenli Zhuang¹

¹State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.

Organic letters

|February 11, 2026

Abstract:

Chlorosulfur compounds, serving as structural cores in numerous bioactive molecules, represent valuable yet synthetically challenging building blocks. Herein, we report a photoinduced 1,2-chlorothiolation of unactivated alkenes enabled by proton transfer and electron transfer processes between hydrochloric acid (HCl) and dimethylsulfoxide (DMSO). This transformation employs inexpensive, readily available, and stable thiophenols as the sulfur source and proceeds without external photocatalysts and metals, constructing chlorosulfur compounds under mild conditions with broad substrate scope, high stereoselectivity, and gram-scale capability.

キーワード:

クロロスルファ化合物の合成光化学有機合成触媒フリーアルケン官能基化

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Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors

Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors

Published on: January 31, 2025

Proton Transfer and Protein Conformation Dynamics in Photosensitive Proteins by Time-resolved Step-scan Fourier-transform Infrared Spectroscopy

Proton Transfer and Protein Conformation Dynamics in Photosensitive Proteins by Time-resolved Step-scan Fourier-transform Infrared Spectroscopy

Published on: June 27, 2014

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