関連する実験動画

Updated: Feb 12, 2026

Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice

Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice

Published on: August 24, 2011

脳室内出血の自発性出血の異なる段階における血清miRNA-210発現

Si-Yuan Chen, He Wang

Clinical laboratory

|February 11, 2026

要旨

Background:

This study investigates the changes in serum miRNA-210 expression at different stages of spontaneous intracerebral hemorrhage (sICH) and their clinical significance.

Methods:

Twenty patients with sICH and admitted to the Neurosurgery Department of the Affiliated Hospital of Beihua University between August 2022 and January 2023 were selected for this study. Venous blood samples were collected on Day 1 (within 12 hours) and Day 7 after disease onset. Serum miRNA-210 expression was quantified using quantitative reverse transcription polymerase chain reaction (qRT-PCR).

Results:

Serum miRNA-210 levels on Day 7 (31.5775 ± 0.13242) were significantly lower than on Day 1 (31.6865 ± 0.1654) in patients with sICH. Results of a paired t-test analysis showed a t value of 2.268, p = 0.035 (p < 0.05).

Conclusions:

In this study, differences in serum miRNA-210 expression at different stages of sICH were found to be significant. Changes in miRNA-210 levels may serve as potential biomarkers for disease progression, providing insights for clinical management.

キーワード:

脳室内出血マイクロRNA-210 バイオマーカー疾患進行臨床管理

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Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation

Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation

Published on: October 15, 2021

Modeling Intracerebral Hemorrhage in Mice: Injection of Autologous Blood or Bacterial Collagenase

Modeling Intracerebral Hemorrhage in Mice: Injection of Autologous Blood or Bacterial Collagenase

Published on: September 22, 2012

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