タンパク質発現の調整可能なツールキットを提供する5´非翻訳領域
Camila Garcia1, Dylan Poch1, Aden M Alemayhu1
1Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, USA.
Molecular biology of the cell
|February 11, 2026
まとめ
研究者らは、一過性トランスフェクション中のタンパク質発現レベルを正確に制御するために、10個のヒト5´非翻訳領域(5´UTR)を開発しました。この方法は、過剰発現アーチファクトを軽減し、さまざまなアプリケーションのタンパク質収量を改善することにより、機能分析を強化します。
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