成人における腸内細菌叢、睡眠の質、および認知機能:システマティックレビュー
Hesam A Varpaei1, Lorraine B Robbins1, Mathew J Reeves2
1College of Nursing, Michigan State University, East Lansing, MI, USA.
Sleep medicine
|February 11, 2026
まとめ
成人の最適な睡眠と認知機能は、腸内細菌の多様性が高いことと関連している。微生物の多様性が高いほど、睡眠の質と認知機能が向上し、脳の接続性によって媒介される。
科学分野:
- 神経科学; 微生物学; 睡眠科学
背景:
- 腸内細菌叢と睡眠の質は、認知機能にとって重要である。
研究 の 目的:
- 成人の認知機能に関連する睡眠の質(効率、総睡眠時間)と腸内細菌叢の組成との関連を調べること。
主な方法:
- システマティックレビューは、Preferred Reporting Items for Systematic Reviews and Meta-Analysesガイドラインに従って実施された。
主要な成果:
- 客観的な睡眠指標は、腸内細菌叢の多様性が高いことと相関し、脳の接続性を介して認知機能に良い影響を与える。
- 慢性的な不眠症は、腸内細菌叢のジスビオーシスと関連している。
- プロバイオティクス補給は、認知機能障害患者の睡眠の質と認知機能を改善した。
結論:
- 睡眠の質、腸内細菌叢、および成人の認知機能の間には、複雑な相互関係が存在する。
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