心房細動アブレーションにおける両房ストレインへの影響:左房と右房の機能の違い
Shinichi Tachibana1, Osamu Inaba1, Yukihiro Inamura1
1Department of Cardiology, Japanese Red Cross Saitama Hospital, Shin-Toshin 1-5, Chu-ou-ku, Saitama, 330-8553, Japan.
Heart rhythm
|February 11, 2026
まとめ
心房細動(AF)のカテーテルアブレーションは、特に右房(RA)において心房機能を著しく改善する。左房(LA)および右房(RA)のストレインは、アブレーション後のAF再発を予測する両方の因子であり、手技転帰の評価におけるそれらの役割を強調している。
科学分野:
- 循環器内科
- 電気生理学
- 医用画像処理
背景:
- 心房細動(AF)のカテーテルアブレーションは心房機能を改善する。
- アブレーション後の心房の室特異的なリモデリングに関する理解は限られている。
研究 の 目的:
- AFアブレーション後の両房ストレインの違いを調査する。
- AF再発に対する心房ストレインの予測値を決定する。
主な方法:
- AFアブレーションを受けた81人の患者の後ろ向き解析。
- 心房ストレイン定量化のための2D心エコー検査による、手技前および手技後の心エコー検査。
主要な成果:
- アブレーション後、左房リザーバー機能ストレイン(LASr)および右房リザーバー機能ストレイン(RASr)の両方に有意な改善が見られた。
- 右房リザーバー機能ストレイン(RASr)は左房リザーバー機能ストレイン(LASr)と比較してより大きな改善が観察された。
- 手技後の左房リザーバー機能ストレイン(LASr)および右房リザーバー機能ストレイン(RASr)は、AF/心房頻拍再発を独立して予測した。
結論:
- AFアブレーションは著明な両房機能回復を促進し、特に右房においてより大きな改善を示した。
- 室特異的な心房ストレイン(LASrおよびRASr)は、逆リモデリングおよび手技転帰予測の感度マーカーとして機能する。
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