福島県の感染症に関連した急性脳炎/脳症: 疫学的な研究

Mitsuaki Hosoya^1,2, Yohei Kume¹, Sakurako Norito¹

¹From the Department of Pediatrics, Fukushima Medical University School of Medicine, Fukushima, Japan.

The Pediatric infectious disease journal

|February 12, 2026

まとめ

福島における急性脳炎の発生率は,年10万人の小児15.2人です. ポリメラーゼ連鎖反応 (PCR) 検査は,関連する感染症の病原体識別を大幅に改善します.

科学分野:

小児科は小児科です.
感染症感染症は感染症です.
エピデミオロジーエピデミオロジー

背景:

日本における急性脳炎/脳病変の発生率と病原体に関するデータは限られている.
以前の疫学調査は,疾患の負担と病因を完全に解明できませんでした.

研究の目的:

福島県における急性脳炎/脳症の流行病学的特徴を決定する.
先進的な診断方法を使用して,関連する感染症や病原体を特定します.

主な方法:

2014年から2024年まで,福島県の16の小児科施設で前向きなアクティブ調査が行われました.
ポリメラーゼ連鎖反応 (PCR) テストは,福島医科大学病院で従来の診断と並行して使用されました.
患者の人口統計,臨床表現,および特定された病原体に関するデータが収集されました.

主要な成果:

感染症に関連した急性脳炎/脳症の106例が11年間で報告され,年間平均9.6例でした.
年間罹患率は5歳未満の10万人に15.2と推定された.
病原体は59.4%の症例で特定され,ヒトヘルペスウイルス-6/7およびインフルエンザウイルスが最も一般的です. PCR検査は,入院患者の病原体検出率を76.0%に引き上げました.

結論:

福島で5歳未満の子供の急性脳炎/脳症の年間発生率は10万人に15.2人です.
総合的なPCR分析は病原体の検出を向上させ,急性脳炎/脳症の理解と管理に不可欠です.
発見は,継続的な監視と高度な診断アプローチの必要性を強調しています.

キーワード:

急性脳炎/脳性病気が発症する.エピデミオロジーエピデミオロジーインシデント率のインシデント率感染症/病原体ポリメラーゼ連鎖反応は,

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