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Updated: Feb 13, 2026

Evaluation of Motor Impairment in C. elegans Models of Amyotrophic Lateral Sclerosis
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Evaluation of Motor Impairment in C. elegans Models of Amyotrophic Lateral Sclerosis

Published on: September 2, 2021

4.9K

トランスクリプトミックのプロファイリングは,アミオトロフィック横筋硬化症におけるミススプライシングと遺伝子融合を明らかにします

Huilin Xu, Tiziana Petrozziello, Adel Boudi

    medRxiv : the preprint server for health sciences
    |February 12, 2026
    PubMed
    まとめ

    アミオトロフィック横筋硬化症 (ALS) のトランスクリプトームは,遺伝子発現の変化だけでなく,広範囲にわたるスプライシングエラーを示しています. 新種のRNA融合を含むこれらの誤差は,この神経変性疾患に対する新しい治療標的を提供します.

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