関連する実験動画

Updated: Feb 13, 2026

Efficient Generation and Editing of Feeder-free IPSCs from Human Pancreatic Cells Using the CRISPR-Cas9 System
09:16

Efficient Generation and Editing of Feeder-free IPSCs from Human Pancreatic Cells Using the CRISPR-Cas9 System

Published on: November 8, 2017

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CRISPR-MiX:人間のiPSCにおけるHDR効率を高めるため,統合された単一鎖ドナー戦略

Rachel Baum1,2, Narasimha Telugu3, Arne A N Bruyneel1,2

  • 1Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.

Molecular therapy. Nucleic acids
|February 12, 2026
PubMed
まとめ

研究者は,正確なゲノム編集と疾患モデリングのために,ヒト誘導多能幹細胞 (iPSCs) のホモロジー誘導修復 (HDR) の効率を大幅に改善する新しい方法であるCRISPR-MiXを開発しました.

キーワード:
CRISPR-Cas9は,CRISPR-Cas9と一致している.DNAが割れ,DNAが割れるDNAの修復 DNAの修復というものです.MT:RNA/DNA編集についてカーディオミオパシー (心筋病)疾患モデリングゲノム編集とはホモロジー・ディレクテッド・修理iPSCsは,iPSCsという名前で,iPSCsは,iPSCsという名前で,iPSCsは,iPSCsという名前で,iPSCsは,iPSCsという名前で,iPSCsは,iPSCsという名前で呼ばれています.多能幹細胞は多能幹細胞である.ssODNN でした.

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During replication, the complementary strands in double-stranded DNA are synthesized at different rates. Replication first begins on the leading strand. Replication starts later, occurs more slowly, and proceeds discontinuously on the lagging strand.
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