Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Polygenic Traits01:18

Polygenic Traits

69.2K
When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
69.2K
Multiple Allele Traits01:49

Multiple Allele Traits

38.2K
The Concept of Multiple Allelism
38.2K
Trait and State Self-Esteem02:08

Trait and State Self-Esteem

11.5K
The term self-esteem is often used generically, to refer to how people feel about themselves. However, according to research, there are three distinct constructs that should not be used interchangeably (Brown & Marshall, 2006). 
11.5K
Traits and States01:17

Traits and States

568
Personality traits represent consistent patterns in behavior, thoughts, and emotions, reflecting an individual's tendencies across various situations. For example, extraversion, a well-known trait, manifests in individuals as talkative, energetic, and enthusiastic behaviors. These traits are stable over time, offering a reliable framework for predicting how people might act in different contexts. However, they do not define every moment of an individual's life. In contrast to traits,...
568
Exceptions to the Octet Rule02:55

Exceptions to the Octet Rule

37.9K
Many covalent molecules have central atoms that do not have eight electrons in their Lewis structures. These molecules fall into three categories:
37.9K
lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

10.0K
In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
10.0K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Longitudinal lineage tracing reveals early clonal attrition during Drosophila midgut aging.

PLoS biology·2026
Same author

Rapid evolution driven by translocation-associated selection during meiosis.

EMBO reports·2026
Same author

Computational approaches for multimodal lineage tracing.

Nature reviews. Genetics·2026
Same author

Mapping the zygote-to-adult developmental cell phylogeny in Arabidopsis thaliana reveals a three-cell rule of branching.

Nature plants·2026
Same author

Homoharringtonine is highly effective against SARS-CoV-2: a potential first-line defense in future coronavirus epidemics.

National science review·2025
Same author

Polyclonal-to-monoclonal transition in colorectal precancerous evolution.

Nature·2024
Same journal

Large-scale Searching for Causal Relationships of Body Mass Index Bridged Modifiable Lifestyle Factors on Colorectal Cancer Risk: A phenome-Wide Mendelian Randomization Study.

Phenomics (Cham, Switzerland)·2026
Same journal

Inulin-Type Hexasaccharide Improves Vascular Dementia by Modulating Sphingomyelin Lipid Metabolism.

Phenomics (Cham, Switzerland)·2026
Same journal

Plasma MicroRNA and Protein Signature Associated with Obesity in the Chinese Han Population Using MicroRNA Omics and Proteomics Analysis of 1026 Subjects.

Phenomics (Cham, Switzerland)·2026
Same journal

Human Cardiac Organoids Reveal Anti-Fibrotic Therapeutic Potential of JAK1/2 Inhibition Following Cryogenic Injury.

Phenomics (Cham, Switzerland)·2026
Same journal

Causal Associations of Red Cell Distribution Width with Rheumatoid Arthritis and Congestive Heart Failure: A Phenome-Wide Mendelian Randomization Study.

Phenomics (Cham, Switzerland)·2026
Same journal

Novel Metabolomic and Adiposity Markers Improve Prediction of Obstructive Sleep Apnea: A Prospective Analysis in the China Human Phenobank.

Phenomics (Cham, Switzerland)·2026
関連記事をすべて見る

関連する実験動画

Updated: Feb 13, 2026

Setup and Execution Of the Blindfolded Code Training Exercise
05:25

Setup and Execution Of the Blindfolded Code Training Exercise

Published on: March 29, 2019

10.0K

フェノタイプ空間における特性のコーディング規則

Jianguo Wang1,2, Xionglei He1,2

  • 1MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275 China.

Phenomics (Cham, Switzerland)
|February 12, 2026
PubMed
まとめ
この要約は機械生成です。

科学者たちは,特徴に影響を与える遺伝的および非遺伝的要因を分離するための新しい方法を開発しました. これは,フェノタイプの特徴は,限られた数の遺伝的次元と無制限の非遺伝的次元によってコードされていることを明らかにします.

キーワード:
脳 脳の脳 脳の脳複合的な特徴の特徴ディメンション分解の分解フェノメ・フェノメ (フェノメ・フェノメ) とはフェノタイプ空間 フェノタイプ空間イーストは酵母です.

さらに関連する動画

Micron-scale Phenotyping Techniques of Maize Vascular Bundles Based on X-ray Microcomputed Tomography
06:21

Micron-scale Phenotyping Techniques of Maize Vascular Bundles Based on X-ray Microcomputed Tomography

Published on: October 9, 2018

9.4K
Imaging and Analysis for Quantifying Maize (Zea mays) Abiotic Stress Phenotypes
06:41

Imaging and Analysis for Quantifying Maize (Zea mays) Abiotic Stress Phenotypes

Published on: March 28, 2025

1.7K

関連する実験動画

Last Updated: Feb 13, 2026

Setup and Execution Of the Blindfolded Code Training Exercise
05:25

Setup and Execution Of the Blindfolded Code Training Exercise

Published on: March 29, 2019

10.0K
Micron-scale Phenotyping Techniques of Maize Vascular Bundles Based on X-ray Microcomputed Tomography
06:21

Micron-scale Phenotyping Techniques of Maize Vascular Bundles Based on X-ray Microcomputed Tomography

Published on: October 9, 2018

9.4K
Imaging and Analysis for Quantifying Maize (Zea mays) Abiotic Stress Phenotypes
06:41

Imaging and Analysis for Quantifying Maize (Zea mays) Abiotic Stress Phenotypes

Published on: March 28, 2025

1.7K

科学分野:

  • 遺伝学とゲノミクス
  • 進化生物学の進化生物学について
  • フェノミクスは,現象学です.

背景:

  • ゲノタイプ-フェノタイプ関係は,現代生物学の中心的なものです.
  • フェノタイプ空間内でフェノタイプ特性がどのようにコードされているかを理解することは限られている.
  • フェノタイプ空間は数学的に遺伝子 (P^G) と非遺伝子 (P^NG) のサブスペースに分けることができます.

研究 の 目的:

  • フェノタイプの特徴に対する遺伝的および非遺伝的影響を分離するために,次元分解法を開発し,適用する.
  • 遺伝的および非遺伝的サブスペースの次元構造を調査する.
  • 酵母と人間の脳の複雑な特徴の遺伝的構造を解明する.

主な方法:

  • 次元分解のための非相関ベースの高次元依存 (UBHDD) を開発し,適用しました.
  • 酵母菌のフェノタイプデータ (約400の特徴,約1000個) にUBHDDを適用した.
  • UBHDDを英国バイオバンクのヒト脳現象型データ (約700の特徴,約26,000人の個体) に適用した.

主要な成果:

  • UBHDDは,酵母とヒトの両方のデータにおいて,遺伝子 (P^G) と非遺伝子 (P^NG) のサブスペースを成功裏に分離しました.
  • 多様な特質のコード化のために,P^Gで限られた数の再発的な潜在次元を特定した.
  • P^NG.で特徴特有の,絶えず増大する次元が実証されています.
  • 人間の脳の非対称性の遺伝子対非遺伝的起源を解明し,新しい遺伝的相関を明らかにした.

結論:

  • フェノタイプの特徴は,限られた共通の遺伝的次元と,無制限の特徴特有の非遺伝的次元によってコードされます.
  • UBHDDは,複雑な特徴の遺伝的および非遺伝的アーキテクチャを解剖するための効果的な方法です.
  • この発見は,新興分野である現象学の基本的ルールを提供しています.