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Updated: Feb 13, 2026

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials
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Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials

Published on: March 9, 2017

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具体的には,細胞状態に反応する合成プロモーターの設計のための体系的な枠組みは,T細胞の枯渇の主要な調節体を明らかにします

Zhaoyu Zhang1, Xiaoyu Qiu1, Hui Ning1

  • 1MOE Key Laboratory of Bioinformatics and Bioinformatics Division Center for Synthetic and Systems Biology Department of Automation Beijing National Research Center for Information Science and Technology Tsinghua University Beijing China.

Quantitative biology (Beijing, China)
|February 12, 2026
PubMed
まとめ

研究者らは,T細胞の枯渇を特に標的とする合成プロモーターを作成するために,機械学習を用いたフレームワークSPECIFICを開発しました. これらのプロモーターは遺伝子発現を制御することができ,T細胞機能不全に対処することによってCAR-T細胞治療を強化するための新しい戦略を提供します.

キーワード:
T細胞の枯渇によるT細胞の枯渇.プロモーターはプロモーターです.合成生物学 合成生物学とは合成プロモーターである.

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