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Updated: Feb 13, 2026

Generating CRISPR/Cas9 Mediated Monoallelic Deletions to Study Enhancer Function in Mouse Embryonic Stem Cells
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Generating CRISPR/Cas9 Mediated Monoallelic Deletions to Study Enhancer Function in Mouse Embryonic Stem Cells

Published on: April 2, 2016

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RNP媒介のCRISPR-Cas9遺伝子削除を用いて,初等マウインの先天性およびメモリT細胞における機能的ドライバをクエリする

Surojit Sarkar, Yevgeniy Yuzefpolskiy, Vandana Kalia

    bioRxiv : the preprint server for biology
    |February 12, 2026
    PubMed
    まとめ

    この研究は,ノックアウトマウスの必要性を回避して,CD8 T細胞の急速な遺伝子削除のためのCRISPR-Cas9方法を導入しています. これにより,感染症や癌に対する免疫反応に関する研究が加速される.

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    Highly Efficient Gene Disruption of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas908:27

    Highly Efficient Gene Disruption of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9

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