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Updated: Feb 13, 2026

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
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cGAS媒介のIFN-Iシグナリングは,薬剤耐性エピレプシーの疾患進行に寄与する

Yige Huang, Li Fan, Man Ying Wong

    bioRxiv : the preprint server for biology
    |February 12, 2026
    PubMed
    まとめ

    薬剤耐性性 (DRE) の進行には,過度に活発なサイクルGMP-AMP合成酵素 (cGAS) が含まれる. DREモデルにおけるcGASを阻害することで,発作と炎症が軽減され,その治療的可能性が強調されました.

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