関連する実験動画

Updated: Feb 13, 2026

In Vivo Imaging Uncovers the Migratory Behavior of Leukocytes within the Joints
10:10

In Vivo Imaging Uncovers the Migratory Behavior of Leukocytes within the Joints

Published on: December 9, 2025

607

統合失調症の新たな治療法の発見:CANDOプラットフォームを使用したマルチターゲットのアプローチ

Yakun Hu, Katherine Elefteriou, Zackary Falls

    bioRxiv : the preprint server for biology
    |February 12, 2026
    PubMed
    まとめ

    CANDOプラットフォームは,マルチターゲットの薬物相互作用を分析することによって,統合失調症のための25の潜在的な再利用薬物を特定しました. このアプローチは,この複雑な神経精神疾患の治療法の発見を促進します.

    さらに関連する動画

    A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia05:51

    A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

    Published on: June 15, 2011

    26.5K
    Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance07:27

    Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

    Published on: August 25, 2021

    2.3K

    関連する概念動画

    Schizophrenia01:17

    Schizophrenia

    Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
    1.0K
    Biological Causes of Schizophrenia01:29

    Biological Causes of Schizophrenia

    Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
    Genetic Factors in Schizophrenia
    The genetic basis of schizophrenia is strongly supported by family and twin...
    656
    Psychological and Sociocultural Causes of Schizophrenia01:29

    Psychological and Sociocultural Causes of Schizophrenia

    Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
    645
    Negative and Cognitive Symptoms of Schizophrenia01:30

    Negative and Cognitive Symptoms of Schizophrenia

    Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
    Negative Symptoms
    Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
    635
    Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

    Positive Symptoms of Schizophrenia: Hallucinations and Delusions

    Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
    Thought Disorders
    Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
    689
    Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

    Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

    Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
    Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
    2.0K