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Updated: Feb 13, 2026

Discovery of New Intracellular Pathogens by Amoebal Coculture and Amoebal Enrichment Approaches
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Discovery of New Intracellular Pathogens by Amoebal Coculture and Amoebal Enrichment Approaches

Published on: October 27, 2013

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リバーシブルワークによる早期濃縮ヒット発見 c(t) メタダイナミクスの見積もり (CTMD)

Venkata Sai Sreyas Adury, Pratyush Tiwary, Xinyu Gu

    bioRxiv : the preprint server for biology
    |February 12, 2026
    PubMed
    まとめ

    薬剤発見スクリーニングにおける早期濃縮のための,物理に基づいた高速なプロトコルであるc(t) ベースのメタダイナミクス (CTMD) を導入します. CTMDは小分子結合剤を正確にランク付けし,AIの方法よりも性能が優れ,かなりのリソースを節約します.

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