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Updated: Jun 5, 2026

Consensus Brain-derived Protein, Extraction Protocol for the Study of Human and Murine Brain Proteome Using Both 2D-DIGE and Mini 2DE Immunoblotting
10:51

Consensus Brain-derived Protein, Extraction Protocol for the Study of Human and Murine Brain Proteome Using Both 2D-DIGE and Mini 2DE Immunoblotting

Published on: April 10, 2014

シングルプレックプロテオミクスは,アルツハイマー病におけるアミロイド微環境の構成と動態を明らかにする

Mengqi Chu, Ju Wang, Jay M Yarbro

    bioRxiv : the preprint server for biology
    |February 12, 2026
    PubMed
    まとめ

    アルツハイマー病のアミロイドプラークは,定義されたプロテオーム (アミロイドーム) を有するダイナミックなハブです. この研究は,早期の免疫およびリソソーム活性化,続いてRNA処理とシナプス経路の関与を明らかにし,プラークの蓄積と細胞イベントをリンクしています.

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