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Updated: Feb 13, 2026

Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research
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Published on: September 8, 2023

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Anti-SARS-CoV-2 Spike Protein モノクローナル抗体におけるACE-2型の酵素活性について

Yufeng Song, Frances Mehl, Tom No

    bioRxiv : the preprint server for biology
    |February 12, 2026
    PubMed
    まとめ

    SARS-CoV-2スパイクタンパク質を標的にする特定の抗体は,ACE2を模倣し,長期のCOVID (LC) 病原体を潜在的に駆動する可能性があります. これらのACE2型アブジメは,ネイティブのACE2とは異なる方法でアニオテンシンIIを分裂させ,COVID-19の続変に関する新しい洞察を提供します.

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    All meta-directing substituents are deactivating groups. These substituents withdraw electrons from the aromatic ring, making the ring less reactive toward electrophilic substitution. For example, the nitration of nitrobenzene is 100,000 times slower than that of benzene because of the deactivating effect of the nitro group. The first step in an electrophilic aromatic substitution is the addition of an electrophile to form a resonance-stabilized carbocation. The energy diagrams for...
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