関連する実験動画

Updated: Feb 13, 2026

Paramagnetic Relaxation Enhancement for Detecting and Characterizing Self-Associations of Intrinsically Disordered Proteins
07:24

Paramagnetic Relaxation Enhancement for Detecting and Characterizing Self-Associations of Intrinsically Disordered Proteins

Published on: September 23, 2021

2.3K

実験的に導かれた複製シミュレーションによる内在的に乱れたタンパク質における適合的異質性を解明する

Wangfei Yang, Sichun Yang, Wenwei Zheng

    bioRxiv : the preprint server for biology
    |February 12, 2026
    PubMed
    まとめ

    私たちは,タンパク質の形状をマッピングする新しい方法を開発し,乱れたタンパク質の隠された状態を明らかにしました. このアプローチは,複数の実験データ型を統合して,タンパク質の動態を正確にモデル化します.

    さらに関連する動画

    Submillisecond Conformational Changes in Proteins Resolved by Photothermal Beam Deflection10:02

    Submillisecond Conformational Changes in Proteins Resolved by Photothermal Beam Deflection

    Published on: February 18, 2014

    9.4K
    Proton Transfer and Protein Conformation Dynamics in Photosensitive Proteins by Time-resolved Step-scan Fourier-transform Infrared Spectroscopy10:03

    Proton Transfer and Protein Conformation Dynamics in Photosensitive Proteins by Time-resolved Step-scan Fourier-transform Infrared Spectroscopy

    Published on: June 27, 2014

    18.4K

    関連する概念動画

    Intrinsically Disordered Proteins02:18

    Intrinsically Disordered Proteins

    Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
    19.6K
    Intrinsically Disordered Proteins02:18

    Intrinsically Disordered Proteins

    2.9K
    Conformity01:20

    Conformity

    Conformity is the change in a person’s behavior to go along with the group, even if that person does not agree with the group.
    48.2K
    Conformations of Butane02:20

    Conformations of Butane

    Unlike ethane and propane that have only two major conformations, butane has more than two conformers. The staggered form of butane in which the bulky methyl groups on the two carbons are placed on opposite sides, that is, at a dihedral angle of 180°, is the lowest energy, most stable form — called the anti conformer. This conformation is stabilized due to the absence of steric repulsion between the largely spaced out methyl groups. The other two staggered conformations are...
    18.3K
    Extrinsic and Intrinsic Pathways of Hemostasis01:20

    Extrinsic and Intrinsic Pathways of Hemostasis

    Blood clotting or coagulation involves extrinsic and intrinsic pathways, which ultimately merge into the common pathway, forming a fibrin clot.
    The Extrinsic Pathway
    The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which...
    13.2K
    The Intrinsic Apoptotic Pathway01:31

    The Intrinsic Apoptotic Pathway

    Internal cellular stress, such as cellular injury or hypoxia, triggers intrinsic apoptosis. The B-cell lymphoma 2 (Bcl-2) family of proteins are the primary regulators of the intrinsic apoptotic pathway. For example, during DNA damage, checkpoint proteins, such as Ataxia Telangiectasia Mutated (ATM protein) and Checkpoints Factor-2 (Chk2) proteins, are activated. These proteins phosphorylate p53 which further activates pro-apoptotic proteins, such as Bax, Bak, PUMA, and Noxa, and inhibits...
    8.7K