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Updated: Feb 13, 2026

CRISPR-Mediated Reorganization of Chromatin Loop Structure
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CRISPR-Mediated Reorganization of Chromatin Loop Structure

Published on: September 14, 2018

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CTCF媒介のクロマチンの組織化の構造的基礎

Manuel Osorio Valeriano, Alexander C Stone, Masahiro Nagano

    bioRxiv : the preprint server for biology
    |February 12, 2026
    PubMed
    まとめ

    CCCTC結合因子 (CTCF) は,ゲノム相互作用と細胞の微分化に不可欠な核粒子のオリゴメリゼーションを通じて染色体構造を組織します. CTCFの相互作用の障害は,遺伝子発現と細胞発達の悪影響を及ぼします.

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