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Updated: Feb 13, 2026

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ASCL1とOLIG2の発現ダイナミクスは,背面前脳における膠質細胞の運命を制御し,地域的な多様性を制御する

Luis E Paez-Beltran, Haojie Chen, Milindu Liyanapathirana

    bioRxiv : the preprint server for biology
    |February 12, 2026
    PubMed
    まとめ

    転写因子ASCL1は,膠質原体の特異性,移動,分化を結びつけ,膠質の発達に不可欠である. そのダイナミックな発現は,脳内のアストロサイトとオリゴデンドロサイトの形成を誘導し,失調はグリオマに寄与する可能性がある.

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