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Updated: Feb 13, 2026

Large-Scale Purification of Porcine or Bovine Photoreceptor Outer Segments for Phagocytosis Assays on Retinal Pigment Epithelial Cells
10:02

Large-Scale Purification of Porcine or Bovine Photoreceptor Outer Segments for Phagocytosis Assays on Retinal Pigment Epithelial Cells

Published on: December 12, 2014

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ペロキシソーム機能障害は,人間の網膜のピグメント上皮質の光受容体の外部のセグメントの代謝を変化させます

Constantin Mouzaaber, Carly B Feldman, Suzette M Huguenin

    bioRxiv : the preprint server for biology
    |February 12, 2026
    PubMed
    まとめ

    ペロキシソーム生体生成障害 (PBD) は網膜の色素の上皮細胞を損なっており,脂質の変化と欠陥性ファゴサイトーシスを引き起こします. この研究では,PBDを調査するためにヒトRPEモデルを開発し,網膜変性のためのメカニズムを明らかにしました.

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