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Updated: Feb 13, 2026

Fabricating a Kidney Cortex Extracellular Matrix-Derived Hydrogel
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Fabricating a Kidney Cortex Extracellular Matrix-Derived Hydrogel

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OLIGODENDROCYTE-DERIVED EXTRACELLULAR MATRIX REJUVENATES COGNITIONON における年齢に関係する変化を考慮する

Amber R Philp, L Remesal, Karishma J B Pratt

    bioRxiv : the preprint server for biology
    |February 12, 2026
    PubMed
    まとめ

    オリゴデンドロサイト由来細胞外マトリックス (ECM) をターゲットにすることで,年齢関連の記憶喪失を逆転させることができます. ハイアルロナンとプロテオグリカンリンクタンパク質2 (HAPLN2) を増加させると認知機能が低下し,減少させると老齢マウスの記憶力が回復する.

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