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Updated: Feb 13, 2026

Techniques to Induce and Quantify Cellular Senescence
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Published on: May 1, 2017

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オシメルチニブ誘発の衰老からの再発的な脱出は,治療抵抗に関連したゲノム不安定性を促進します

Hayley Mcdaid, Nazia Jamil, Qualia Hooker

    bioRxiv : the preprint server for biology
    |February 12, 2026
    PubMed
    まとめ

    EGFR変異性非小細胞肺がんに対するオシメルチニブ治療は,細胞老化を誘発する可能性があります. この老化を回避すると,ゲノム不安定性を通じた耐性が獲得され,細胞毒性療法がより効果的かもしれないことを示唆します.

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