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Updated: Feb 13, 2026

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DLL3を標的とするVHHベースのCAR-T細胞は,小細胞肺がんモデルにおいて高い有効性を示しています

Han Guo1, Chunjiang Yue2, Di Ma1

  • 1Shanghai Jiao Tong University Shanghai China.

Molecular cancer therapeutics
|February 12, 2026
PubMed
まとめ

この研究では,小細胞肺がん (SCLC) に対する新しい抗DLL3 VHH-CAR T細胞を開発しました. これらのエンジニアリングされたT細胞は,実験室試験および動物モデルで強力な腫瘍破壊能力を示し,DLL3発現がんに対する有望な新しい免疫療法を提供しました.

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