スプリット・太さの皮膚移植不全のベースラインリスク要因: 遡及的なコホート研究

Eve Kinnunen^1,2, Johanna Raukola^2,3, Paavo Paajanen^2,4

¹Department of Plastic Surgery, University of Helsinki and Helsinki University Hospital, P.O. Box 281, 00029 HUS, Helsinki Finland.

Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society

|February 12, 2026

まとめ

分厚い皮膚移植の失敗の予測要因を特定することは,傷の治癒に不可欠です. 外周動脈疾患,糖尿病,足の位置が障害リスクを高め,胸の傷やトラウマが低下させる.

科学分野:

整形外科手術についてです.
傷の癒し傷の癒し
再生医学は,再生医療である.

背景:

スプリット厚さの皮膚移植は,複雑な傷に対する標準的な処置です.
皮膚移植の失敗と治癒の遅延の予測要因については,さらなる解明が必要である.

研究の目的:

スプリット・太さの皮膚移植不全のベースライン予測要因を特定するために.
移植後の傷の治癒が遅れる予測要因を特定するために.

主な方法:

分厚い皮膚移植 (2009年−2019年) を受けた1011人の成人の患者で1484の傷を対象とした単一センターでの遡及的研究.
グラフトの故障は,完全な損失または再操作の必要性として定義されます.
ロジスティック回帰とコックス比例リスク分析を用いた.

主要な成果:

移植不全は25.9%で,再手術は20.0%で必要だった.
外周動脈疾患,糖尿病,免疫抑制薬,足の位置が,移植不全のリスクを大幅に増加させた.
治癒の遅延に関連する要因には,足の位置,より長い傷口の持続時間,腫れ,外周動脈疾患,抗精神病薬の使用,および併合性疾患が含まれています.

結論:

皮膚移植後の不良の結果をもたらすいくつかのリスク要因が特定されました.
患者の併発症および傷口病因の術前評価は,手術計画と結果を最適化するために不可欠です.

キーワード:

スプリット厚さの皮膚移植.失敗失敗失敗失敗結果,結果,結果として.リスクファクターの危険因子皮膚移植皮膚の移植皮膚の移植

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