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Updated: Feb 13, 2026

Primer Extension Capture: Targeted Sequence Retrieval from Heavily Degraded DNA Sources
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Primer Extension Capture: Targeted Sequence Retrieval from Heavily Degraded DNA Sources

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標的配列キャプチャ (TSC) の適用は,抗体産生細胞系統の遺伝的特徴化のためである

Sofie A O'Brien1, Jake T Leinas1, Jodi Grantham1

  • 1Bioprocess Research and Development, Pfizer Inc., Bothell, Washington, USA.

Biotechnology journal
|February 12, 2026
PubMed
まとめ

次世代配列解析 (NGS) は,発達の初期に生理療法用生産細胞系の遺伝的安定性を評価するための強力な方法を提供します. このアプローチは,遺伝的比較性を確保し,商業的製造のための細胞系選択に関連するリスクを軽減します.

キーワード:
CHO細胞とは遺伝的特徴化 遺伝的特徴化次世代のシーケンシングです.ターゲティングされたシーケンスキャプチャ.

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