複雑な肝臓および周辺肝臓腫瘍に対する外科的アプローチ:アンテ・シタムとエクス・シトゥのテクニックによる単一センターでの経験
Ammar Khan1,2, Bjarte Fosby1, Sheraz Yaqub2,3
1Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.
International journal of surgery (London, England)
|February 12, 2026
まとめ
Ante situmおよびex situの肝臓手術は,切除できない肝臓腫瘍の有効な治療法を提供します. このアプローチは,管理可能なリスクと良好な長期生存率,特に良性および原発性悪性腫瘍を示す.
科学分野:
- 肝臓・胆管の手術は肝臓・胆管の手術である.
- 外科腫瘍学の外科手術である.
- 移植手術 移植手術 移植手術 移植手術
背景:
- Ante situmおよびex situの肝臓手術は,切除不能の肝臓腫瘍に対する高度な手順です.
- 歴史的に,これらの複雑な手術は,高い罹病率と死亡率の課題に直面してきました.
- この研究は,これらの特殊な肝臓手術の結果を評価しています.
研究 の 目的:
- ante situmおよびex situ肝臓外科手術に関連した手術後の罹病率と死亡率を評価する.
- これらの複雑な肝臓切除後の長期的な生存率を評価するために.
- 肝臓腫瘍の挑戦的な症例に対するこれらの外科的技法の有効性を決定する.
主な方法:
- オスロ大学病院で単一センターコホート研究が行われました.
- データは,2001年から2023年の間にアンテ・シトゥーおよびエク・シトゥー肝臓手術を受けた連続した患者から収集されました.
- 生存と合併症を含む患者のアウトカムが分析されました.
主要な成果:
- 35人の患者が手術を受け,診断には原発性肝臓がん,結腸直腸肝臓転移,良性疾患が含まれていました.
- 90日間の死亡率は5.7%でした.
- 5年生存率は,良性疾患では100%,原発性腫瘍では49.4%,転移性がんでは0%でした.
結論:
- Ante situmおよびex situの肝臓手術は,切除不能の肝臓腫瘍を有する慎重に選択された患者にとって実現可能である.
- これらの手順は,管理可能な外科手術後のリスクを提供します.
- 特に良性および原発性肝臓悪性腫瘍については,長期的に見ると有望な結果が見られた.
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