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Updated: Feb 13, 2026

Perturbing Endothelial Biomechanics via Connexin 43 Structural Disruption
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セマフォリン3Aは内皮構造とリソソーム機能を破壊する:高血圧妊娠におけるインヴィトロメカニズムとインビボエビデンス

Gabriella Ferretti1, Sara Serafini1,2, Laura Sarno3

  • 1Unit of Pharmacology, Department of Neuroscience, School of Medicine, University of Naples, "Federico II", 80131, Naples, Italy.

Clinical science (London, England : 1979)
|February 12, 2026
PubMed
まとめ

セマフォリン3A (SEMA3A) は高血圧妊娠,特に胎児の成長制限で上昇します. この分子は内皮細胞の機能を破壊し,妊娠中の血管機能不全の役割を示唆しています.

キーワード:
細胞骨格のダイナミクス内皮機能不全は,内皮の機能不全である.胎児成長制限 胎児成長制限妊娠中の高血圧障害ライソソームの密輸ニューロピリン 1 1神経血管シグナリングセマフォリン 3A

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