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Updated: Feb 13, 2026

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BICC1はPKD1とPKD2と相互作用し,ADPKDにおける細胞生成を誘導する

Uyen Tran1, Andrew J Streets2, Devon Smith2

  • 1Department of Heart, Blood & Kidney Research, Cleveland Clinic Research, Cleveland Clinic, Cleveland, United States.

eLife
|February 12, 2026
PubMed
まとめ

Bicc1タンパク質は,自己相性多囊性腎臓病 (ADPKD) に関するタンパク質であるポリシスティン1とポリシスティン2と相互作用する. BICC1の変異はADPKDの重症度を悪化させ,RNA代謝が疾患変異における役割を示唆する可能性がある.

キーワード:
ADPKDD についてEO-ADPKDD についてRNAの代謝,RNAの代謝についてVEO-ADPKDD でした.細胞生物学 細胞生物学慢性腎臓病 慢性腎臓病 慢性腎臓病 慢性腎臓病 慢性腎臓病 慢性腎臓病 慢性腎臓病発達生物学 発達生物学とは遺伝子組み換え剤 遺伝子組み換え剤 遺伝子組み換え剤人間,人,人,人.マウス マウス マウス マウス マウストランスレーション・コントロールクセノプス (Xenopus) とは

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