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Updated: Feb 14, 2026

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
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Published on: November 22, 2014

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CRISPRの活性化のためのバクテリアの共因子

Zhipeng Wang1, Yujue Wang1, Quanjiang Ji1,2,3

  • 1School of Physical Science and Technology & State Key Laboratory of Advanced Medical Materials and Devices, ShanghaiTech University, Shanghai 201210, China.

Biochemistry
|February 12, 2026
PubMed
まとめ

細菌のチオレドキシン (TrxA) は,Cas12p酵素のDNA分裂活動を強化する. この相互作用は,再酸化反応に敏感な結合領域によって媒介され,CRISPR-Casシステムが補助因子によって調節されていることを明らかにします.

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