妊産婦の糖尿病と早期の神経発達: 糖尿病タイプによる子育てにおける異なったマイルストーンの達成
Liya Kerem1, Joshua Guedalia2,3, Michal Lipschuetz3,4,5
1Division of Pediatric Endocrinology, Department of Pediatrics, Hadassah Medical Center, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
Diabetes care
|February 12, 2026
まとめ
母親の糖尿病,特に妊娠前のタイプは,子供の発達におけるマイルストーンの遅延と関連しています. 妊娠糖尿病は,細部運動の遅延とわずかな関連性も示した.
科学分野:
- 発達小児科 発達小児科
- 妊産婦・胎児医学について
- 神経発達障害 神経発達障害とは
背景:
- 母親の糖尿病は,子孫の神経発達障害の既知の危険因子です.
- 早期発達におけるマイルストーンの達成に対する母性糖尿病の影響は不明である.
研究 の 目的:
- 母親の糖尿病 (妊娠期,タイプ1,タイプ2) と子孫の発達における遅延のマイルストーンとの関連を調査する.
- 異なるタイプの母体糖尿病と乳児の性別におけるリスクを比較する.
主な方法:
- 2018年から2021年の間に生まれた466,462人の乳児を対象とした全国的な遡及コホート研究.
- 関連付けられた全国的な母子保健データと退院データを使用した.
- 構造化された看護師評価を通じて,最大24ヶ月までの発達マイルストーンを評価しました.
主要な成果:
- 妊娠糖尿病 (1型および2型) は,言語,パーソナル・ソーシャル,および総運動能力の遅延のリスクを大幅に増加させた.
- 1型糖尿病の母親の子孫は,特に女性の乳児は,最も高いリスクを持っていた.
- 妊娠中糖尿病 (GDM) は,細部運動の遅延のわずかな増加と関連していました.
結論:
- 妊娠中の母性糖尿病は,糖尿病のタイプ,発達領域,乳児の性別に左右される方法で,マイルストーン達成の遅延と関連しています.
- 長期的な結果を理解し,被曝した子供に対する早期介入の情報を提供するために,さらなる研究が必要である.
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