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Updated: Feb 14, 2026

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抗ウイルス防御経路に対するポックスウイルスの攻撃は,エフェクタが誘発するNF-κB反応を誘発する

Brenna C Remick1, Joshua Q Mao1, Andrew G Manford1,2

  • 1Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.

Science (New York, N.Y.)
|February 12, 2026
PubMed
まとめ

科学者たちは,ウイルスエフェクターをスクリーニングすることによって,ヒトの病原体感知経路を見つける新しい方法を発見しました. 彼らは,核因子 κB (NF-κB) の負のレギュレータをターゲットにすることで,抗ウイルス免疫を活性化するポックスウイルスエフェクターを発見しました.

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