Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Vaccinations01:51

Vaccinations

51.9K
Overview
51.9K
Cancer Vaccines01:30

Cancer Vaccines

1.1K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.1K
Other Nuclides: 31P, 19F, 15N NMR01:16

Other Nuclides: 31P, 19F, 15N NMR

804
Many organic, inorganic, and biological molecules contain spin-half nuclei such as nitrogen-15, fluorine-19, and phosphorus-31. As a result, NMR studies of these nuclei have found extensive applications in chemical and biological research.
While fluorine-19 and phosphorous-31 have high natural abundances (100%) and positive gyromagnetic ratios, nitrogen-15 has a low natural abundance and a negative gyromagnetic ratio. However, nitrogen-15 is still preferred over nitrogen-14 (which has a...
804
Atomic Radii and Effective Nuclear Charge03:08

Atomic Radii and Effective Nuclear Charge

62.3K
The elements in groups of the periodic table exhibit similar chemical behavior. This similarity occurs because the members of a group have the same number and distribution of electrons in their valence shells.
62.3K
Buffer Effectiveness02:19

Buffer Effectiveness

55.6K
Buffer solutions do not have an unlimited capacity to keep the pH relatively constant . Instead, the ability of a buffer solution to resist changes in pH relies on the presence of appreciable amounts of its conjugate weak acid-base pair. When enough strong acid or base is added to substantially lower the concentration of either member of the buffer pair, the buffering action within the solution is compromised.
The buffer capacity is the amount of acid or base that can be added to a given volume...
55.6K
Kinetic Molecular Theory and Gas Laws Explain Properties of Gas Molecules02:34

Kinetic Molecular Theory and Gas Laws Explain Properties of Gas Molecules

37.6K
The test of the kinetic molecular theory (KMT) and its postulates is its ability to explain and describe the behavior of a gas. The various gas laws (Boyle’s, Charles’s, Gay-Lussac’s, Avogadro’s, and Dalton’s laws) can be derived from the assumptions of the KMT, which have led chemists to believe that the assumptions of the theory accurately represent the properties of gas molecules.
37.6K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Hour of the wolf.

Science (New York, N.Y.)·2026
Same author

Malaria may cause long-term brain deficits, study shows.

Science (New York, N.Y.)·2026
Same author

'Truly spectacular' drug for sleeping sickness simplifies treatment, raising hopes for eradication.

Science (New York, N.Y.)·2026
Same author

Abandoned antiviral shows promise against dengue.

Science (New York, N.Y.)·2025
Same author

New study fuels debate over lifesaving antibiotic strategy for children in Africa.

Science (New York, N.Y.)·2025
Same author

Autism initiative embraces little-tested vitamin as a treatment.

Science (New York, N.Y.)·2025

関連する実験動画

Updated: Feb 14, 2026

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19
08:48

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19

Published on: February 16, 2022

3.5K

COVID-19ワクチンによる稀で危険な副作用について説明

Gretchen Vogel, Kai Kupferschmidt

    Science (New York, N.Y.)
    |February 12, 2026
    PubMed
    まとめ

    科学者たちは,アデノウイルスベースのワクチンによる稀な血栓と出血の原因を特定しました. この研究は,これらの重度の有害事象の背後にあるメカニズムを明らかにし,ワクチンの安全性に関する理解を向上させます.

    科学分野:

    • 免疫学 免疫学とは
    • ウイルス学 ウイルス学 ウイルス学
    • 血液学 ヘマトロジ

    背景:

    • アデノウイルスベースのワクチンは,遺伝子の伝達のためにウイルスベクトルを利用します.
    • ワクチン接種後,血栓塞栓症候群 (TTS) による血栓形成の希少な症例が報告されています.
    • TTSの病因的要因を理解することは,公衆衛生にとって極めて重要です.

    研究 の 目的:

    • アデノウイルスベクトルワクチンと重度の血栓性および出血事件を結びつける根本的なメカニズムを解明する.
    • ワクチンが誘発する免疫性血栓性血栓性小便症の原因となる特定の分子経路を特定する.

    主な方法:

    • 患者の免疫反応と血液サンプルを分析する.
    • ワクチン成分と血小板の相互作用を調査するインビトロ研究.
    • 補完体系の活性化と抗体形成の調査.

    主要な成果:

    • 原因は,血小板素因子4 (PF4) を標的とした特定の免疫反応が原因と特定されました.
    • アデノウイルスタンパク質がPF4に結合し,免疫原性複合体を形成することが判明しました.
    • これらの複合体は血小板の活性化と集積を誘発し,血栓と出血につながった.

    さらに関連する動画

    High-Speed Human Temporal Bone Sectioning for the Assessment of COVID-19-Associated Middle Ear Pathology
    03:42

    High-Speed Human Temporal Bone Sectioning for the Assessment of COVID-19-Associated Middle Ear Pathology

    Published on: May 18, 2022

    2.7K
    A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
    06:46

    A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

    Published on: July 5, 2022

    3.4K

    関連する実験動画

    Last Updated: Feb 14, 2026

    Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19
    08:48

    Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19

    Published on: February 16, 2022

    3.5K
    High-Speed Human Temporal Bone Sectioning for the Assessment of COVID-19-Associated Middle Ear Pathology
    03:42

    High-Speed Human Temporal Bone Sectioning for the Assessment of COVID-19-Associated Middle Ear Pathology

    Published on: May 18, 2022

    2.7K
    A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
    06:46

    A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

    Published on: July 5, 2022

    3.4K

    結論:

    • この研究では,アデノウイルスベクトルが,ヘパリン誘発性血小板閉塞症に類似した,PF4に対する抗体を誘発することが明らかになりました.
    • このメカニズムは,観察された希少だが重度の血液凝固および出血の合併症を説明する.
    • 発見は,リスク軽減戦略と改善されたワクチンの開発のための基礎を提供します.