関連する実験動画

Updated: Feb 14, 2026

Biochemical Assays for Analyzing Activities of ATP-dependent Chromatin Remodeling Enzymes
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人間のBAF染色体リモデレータは,先駆的な転写因子OCT4-SOX2によって結合された核細胞を処理する

Joscha Weiss1, Luca Vecchia2, David Domjan3

  • 1Institute for Cancer Research (ISREC), Swiss Federal Institute of Technology Lausanne (EPFL), Station 19, CH-1015 Lausanne, Switzerland; Friedrich Miescher Institute for Biomedical Research, Fabrikstrasse 24, 4058 Basel, Switzerland; University of Basel, Petersplatz 10, 4001 Basel, Switzerland.

Molecular cell
|February 12, 2026
PubMed
まとめ

OCT4-SOX2のような先駆的な転写因子 (TF) は,核細胞体上のBAF複合体と相互作用する. BAF複合体は2つの方向性を用いて,TF結合に影響を与え,クロマチンの改造方向を潜在的に変化させる.

キーワード:
BAFは,BAFが,BAFが,BAFが,BAFが,BAFが,BAFが,BAFが,BAFが,BAFが,BAFが,BAFが,BAFが,BAFが,BAFが,BAFは,BAFが,BAFは,BAFは,BAFは,BAFは,BAFは,BAFは,BAFは,BAFは,BAFは,BAFは,BAFは,BAFはオクト4 オクト4 オクト4SOX2は,SOX2というSWI/SNFはSNFと一致しています.クロマチンのリモデレータークリオ・エム・エム (cryo-EM) とは遺伝子調節 遺伝子調節ヌクレオソームの核子である.先駆的なTFでした.単一分子FRETETは,単一分子FRETであるため,

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