多発性骨髄腫の患者で未溶解のエトポシドを投与した後の中枢静脈カテーターの破裂:症例報告
Ting Lei1, Linbo Zhang2, Jiayu Zhou3
1Department of Hepato-Biliary-Pancreatic Surgery, Suining Central Hospital, Sichuan, China.
The journal of vascular access
|February 12, 2026
まとめ
中枢静脈カテーテル (CVC) の破裂は,エトポシド (VP-16) の溶媒分解により発生しました. このケースは,化学療法中に慎重にカテーテル材料の選択とCVC損傷のモニタリングの必要性を強調しています.
科学分野:
- 腫瘍学 腫瘍学
- 医療機器 医療機器について
- 薬理学 薬理学とは
背景:
- 中枢静脈カテーテル (CVC) は,長期の化学療法投与に不可欠です.
- カテーテル破裂は珍しいが深刻な合併症です.
- ポリウレタンキャセターは一般的に使用されていますが,化学分解に敏感かもしれません.
研究 の 目的:
- 中枢静脈カテーテル破裂の症例を報告する.
- エトポシド輸液中のカテーテル機能不全の原因を調査する.
- 医療機器における材料互換性の重要性を強調する.
主な方法:
- 化学療法を受けている多発性骨髄腫患者の症例報告.
- カテーテル機能不全の分析と,除去されたカテーテルの身体検査.
- カテーターの整合性と静脈血栓症を評価するための放射線と超音波画像検査.
主要な成果:
- ポリウレタン製のCVCは,未溶解エトポシド (VP-16) に長時間曝露した結果,縦断的に破裂した.
- 破裂はカテーテル機能障害,局所的な症状を引き起こし,静脈血栓症と関連していました.
- ヒストロジカル検査では,脆い断片化が示され,溶媒による分解を示唆した.
結論:
- 希釈されていないエトポシドは,ポリウレタン中央静脈カテーターの溶媒誘発性分解を引き起こす可能性があります.
- カテーテル機能不全の症状を早期に認識することは極めて重要です.
- 合併症を予防するために,化学療法剤と互換性のあるカテーテル材料の慎重な選択が不可欠です.
さらに関連する動画
09:57A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
13.8K
09:17Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness
Published on: May 2, 2017
9.4K
関連する概念動画
Data Reporting and Recording
5.5K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.5K
Measures of Central Tendency
21.5K
The "center" of a data set is also a way of describing location. The two most widely used measures of the "center" of the data are the mean (average) and the median. The words "mean" and "average" are often used interchangeably. The substitution of one word for the other is common practice. The technical term is "arithmetic mean" and "average" is technically a center location. However, in practice among non-statisticians,...
21.5K
The Central Dogma
140.1K
Overview
140.1K
Venous Return
12.6K
The circulatory system plays a crucial role in ensuring the optimal functioning of the human body. One of its critical components is venous return - the process that completes the blood circulation cycle. This article will delve into the concept of venous return, how it works, and its significance to our health.
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
12.6K
Venous Thrombosis I: Introduction
489
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
489
Types of Reports I: Hands-off Report
1.6K
A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
Following are the key components and categories of hand-off reports:
Purpose and Process:
1.6K
