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Updated: Feb 14, 2026

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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バイオミメティック酸性条件下におけるインドールモノアミンとトリプトラントリンのスピロサイクルアドクト形成

Kang Mu Kwon1, Kyounghoon Lee2, Sin Young Park1

  • 1Department of Pharmacy and Research Institute of Pharmaceutical Sciences, Woosuk University, Wanju, Jeonbuk 55338, Republic of Korea.

Journal of natural products
|February 12, 2026
PubMed
まとめ

インディゴナチュラリスのトリプトンサリンは,ヒトの代謝産物と反応して,新しい抗炎症化合物を形成します. これらのスパイロサイクリックアダクトは,潰瘍性大腸炎のような炎症性疾患の治療の可能性を示しています.

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