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Updated: Feb 14, 2026

Aptamer-Based Target Detection Facilitated by a 3-Stage G-Quadruplex Isothermal Exponential Amplification Reaction
03:38

Aptamer-Based Target Detection Facilitated by a 3-Stage G-Quadruplex Isothermal Exponential Amplification Reaction

Published on: October 6, 2022

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コロナウイルスの炎症を標的とする:新興の脅威に対するアプタマーベースの戦略

Yongyun Zhao1,2, Gang Yang1,2, Zhaoyong Zhang3

  • 1Department of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital; Department Center for Functional Genomics and Bioinformatics, College of Life Science, Sichuan University, Chengdu, Sichuan, PR China.

Signal transduction and targeted therapy
|February 12, 2026
PubMed
まとめ

新しいDNAアプタマーNApt8-3は,保存されたコロナウイルス核カプシドタンパク質を標的とし,炎症を抑制します. 併用治療薬であるcircSASONは,マウスのSARS-CoV-2を減少させ,将来のパンデミック治療の可能性を明らかにした.

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